NEW DELHI: Even as the world grapples with the challenge of vaccine-derived poliovirus (VDPV), instances of which have been reported sporadically from countries using the oral polio vaccine, including India, a case has been reported from Kerala where the VDPV was transmitted from an immune-deficient child to his healthy father.
The discovery was made during an exercise – undertaken by ICMR-National Institute of Virology, Mumbai, and ICMR-National Institute of Immunohematology and WHO among others – in two phases in 2022, according to a study published in the journal Vaccines.
As many as 157 children with inborn errors of immunity or IEI were screened for the excretion of poliovirus/non-polio entero-viruses in different parts of the country.
The study doesn’t detail father’s, an asymptomatic 32-year-old male, recovery but points out that iVDPVs are likely to be a major threat for the re-emergence of poliovirus and suggests a long-term plan for iVDPV surveillance to ensure sustainability in post-polio eradication phase.
The discovery was made during an exercise – undertaken by ICMR-National Institute of Virology, Mumbai, and ICMR-National Institute of Immunohematology and WHO among others – in two phases in 2022, according to a study published in the journal Vaccines.
As many as 157 children with inborn errors of immunity or IEI were screened for the excretion of poliovirus/non-polio entero-viruses in different parts of the country.
The study doesn’t detail father’s, an asymptomatic 32-year-old male, recovery but points out that iVDPVs are likely to be a major threat for the re-emergence of poliovirus and suggests a long-term plan for iVDPV surveillance to ensure sustainability in post-polio eradication phase.